anti-M-CSF antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG66021
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Size:
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes M-CSF |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, Neut, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | M-CSF |
| 抗原物种 | Mouse |
| 抗原 | E. coli derived recombinant Mouse M-CSF. (MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP) |
| 偶联标记 | Un-conjugated |
| 別名 | Macrophage colony-stimulating factor 1; CSF-1; Lanimostim; M-CSF; MCSF |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P07141 Mouse Macrophage colony-stimulating factor 1 |
|---|---|
| 基因名称 | Csf1 |
| 全名 | colony stimulating factor 1 (macrophage) |
| 背景介绍 | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| 生物功能 | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. [UniProt] |
| 预测分子量 | 60 kDa |
| 翻译后修饰 | N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated. |
检测图片 (3)
ARG66021 anti-M-CSF antibody WB image
Western blot: 250 - 0.24 ng of Mouse M-CSF stained with ARG66021 anti-M-CSF antibody, under non-reducing conditions.
ARG66021 anti-M-CSF antibody standard curve image
Sandwich ELISA: ARG66021 anti-M-CSF antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66022 anti-M-CSF antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
ARG66021 anti-M-CSF antibody WB image
Western blot: 250 - 0.24 ng of Mouse M-CSF stained with ARG66021 anti-M-CSF antibody, under reducing conditions.
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