anti-MCF2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原:
- 偶联标记:
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Brand:
CAT.NO. : ARG44337
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Product Details
概述
| 产品描述 | Rabbit Polyclonalrecognizes MCF2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MCF2 |
| 抗原 | Recombinant fusion protein of human MCF2(aa sequence 872-1001) |
| 偶联标记 | Un-conjugated |
| 別名 | MCF2; MCF.2 Cell Line Derived Transforming Sequence; DBL; ARHGEF21; Oncogene MCF2 (Oncogene DBL); Proto-Oncogene MCF-2; Proto-Oncogene DBL |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS (pH 7.3) and 0.01% Sodium azide. |
| 抗菌剂 | 0.01% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MCF2 |
| 全名 | MCF.2 Cell Line Derived Transforming Sequence |
| 背景介绍 | The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity. |
| 生物功能 | Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42. |
| 细胞定位 | Cytoplasm, Membrane |
| 预测分子量 | 108 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (1)
ARG44337 anti-MCF2 antibody WB image
Western blot: HT-29 stained with ARG44337 anti-MCF2 antibody at 1:3000 dilution.
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