anti-MED28 / EG1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MED28 / EG1
  • 反应物种: Hu
  • 应用: FACS, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MED28 / EG1
  • 抗原物种: Human
  • 抗原: Human MED28 / EG1 recombinant protein (aa. sequence: M1-T178).
  • Brand:
CAT.NO. : ARG44569
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MED28 / EG1
反应物种Hu
应用FACS, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MED28 / EG1
抗原物种Human
抗原Human MED28 / EG1 recombinant protein (aa. sequence: M1-T178).
偶联标记Un-conjugated
別名MED28; Mediator Complex Subunit 28; Magicin 2; EG1; Mediator Of RNA Polymerase II Transcription Subunit 28; Merlin And Grb2-Interacting Cytoskeletal Protein; Tumor Angiogenesis Marker EG-1; Endothelial-Derived Protein 1; DKFZP434N185; Mediator Of RNA Polymerase II Transcription, Subunit 28 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription, Subunit 28 Homolog; Endothelial-Derived Gene 1; 1500003D12Rik
应用说明
应用建议
应用推荐稀释比
FACS1-3 µg/10^6 cells
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
抗菌剂4% Trehalose
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 80306 Human MED28

Swiss-port # Q9H204 Human Mediator of RNA polymerase II transcription subunit 28

基因名称MED28
全名Mediator Complex Subunit 28
背景介绍Predicted to enable actin binding activity. Predicted to act upstream of or within negative regulation of smooth muscle cell differentiation and stem cell population maintenance. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
生物功能Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. [Uniprot]
细胞定位Cytoplasm, Membrane, Nucleus. [Uniprot]
预测分子量20 kDa
检测图片 (1)
  • ARG44569 anti-MED28 / EG1 antibody WB image

    Western blot: K562 and HepG2 stained with ARG44569 anti-MED28 / EG1 antibody at 0.5 μg/mL dilution.

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