anti-MHC Class I H2 Db antibody [28-14-8] (low endotoxin)
CAT.NO. : ARG21075
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概述
产品描述 | Azide free and low endotoxin Mouse Monoclonal antibody [28-14-8] recognizes MHC Class I H2 Db |
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反应物种 | Ms |
应用 | BL, FACS, IHC-Fr, IP |
特异性 | The clone 28-14-8 binds to the α3 domain of H-2Db in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. 28-14-8 can block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 28-14-8 |
同位型 | IgG2a, kappa |
靶点名称 | MHC Class I H2 Db |
抗原物种 | Mouse |
抗原 | C3H.SW mouse splenocytes |
偶联标记 | Un-conjugated |
別名 | H-2 class I histocompatibility antigen, D-B alpha chain; H2-D; B; H-2D |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化说明 | Low endotoxin |
缓冲液 | PBS |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P01899 Mouse H-2 class I histocompatibility antigen, D-B alpha chain |
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基因名称 | H2-D1 |
全名 | histocompatibility 2, D region locus 1 |
生物功能 | Involved in the presentation of foreign antigens to the immune system. [UniProt] |
预测分子量 | 41 kDa |
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