anti-MHC Class I H2 Db antibody [28-14-8] (low endotoxin)

Key features and details

  • 产品描述: Azide free and low endotoxin Mouse Monoclonal antibody [28-14-8] recognizes MHC Class I H2 Db
  • 反应物种: Ms
  • 应用: BL, FACS, IHC-Fr, IP
  • 特异性: The clone 28-14-8 binds to the α3 domain of H-2Db in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. 28-14-8 can block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 28-14-8
  • 同位型: IgG2a, kappa
  • 靶点名称: MHC Class I H2 Db
  • Brand:
CAT.NO. : ARG21075
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Product Details
概述
产品描述Azide free and low endotoxin Mouse Monoclonal antibody [28-14-8] recognizes MHC Class I H2 Db
反应物种Ms
应用BL, FACS, IHC-Fr, IP
特异性The clone 28-14-8 binds to the α3 domain of H-2Db in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. 28-14-8 can block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells.
宿主Mouse
克隆Monoclonal
克隆号28-14-8
同位型IgG2a, kappa
靶点名称MHC Class I H2 Db
抗原物种Mouse
抗原C3H.SW mouse splenocytes
偶联标记Un-conjugated
別名H-2 class I histocompatibility antigen, D-B alpha chain; H2-D; B; H-2D
应用说明
应用建议
应用推荐稀释比
BLAssay-dependent
FACS
IHC-FrAssay-dependent
IPAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明Low endotoxin
缓冲液PBS
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14964 Mouse H2-D1

Swiss-port # P01899 Mouse H-2 class I histocompatibility antigen, D-B alpha chain

基因名称H2-D1
全名histocompatibility 2, D region locus 1
生物功能Involved in the presentation of foreign antigens to the immune system. [UniProt]
预测分子量41 kDa
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