anti-MMP10 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MMP10
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MMP10
  • 抗原物种: Human
  • 抗原: Recombinant protein corresponding to Y239-C476 of Human MMP10.
  • Brand:
CAT.NO. : ARG59021
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MMP10
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MMP10
抗原物种Human
抗原Recombinant protein corresponding to Y239-C476 of Human MMP10.
偶联标记Un-conjugated
別名SL-2; STMY2; Transin-2; EC 3.4.24.22; Matrix metalloproteinase-10; MMP-10; Stromelysin-2
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
应用说明IHC-P: Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 117061 Rat MMP10

GeneID: 17384 Mouse MMP10

GeneID: 4319 Human MMP10

基因名称MMP10
全名matrix metallopeptidase 10
背景介绍Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
生物功能Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. [UniProt]
细胞定位Secreted, extracellular space, extracellular matrix. [UniProt]
预测分子量54 kDa
检测图片 (5)
  • ARG59021 anti-MMP10 antibody ICC/IF image

    Immunofluorescence: A549 cells stained with ARG59021 anti-MMP10 antibody.

  • ARG59021 anti-MMP10 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon cancer tissue. Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then staind with ARG59021 anti-MMP10 antibody at 1 μg/ml, overnight at 4°C.

  • ARG59021 anti-MMP10 antibody WB image

    Western blot: 50 µg of samples under reducing conditions. Rat cardiac muscle and Mouse cardiac muscle lysates stained with ARG59021 anti-MMP10 antibody at 0.5 µg/ml, overnight at 4°C.

  • ARG59021 anti-MMP10 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human mammary cancer tissue. Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG59021 anti-MMP10 antibody at 1 μg/ml, overnight at 4°C.

  • ARG59021 anti-MMP10 antibody WB image

    Western blot: 50 µg of samples under reducing conditions. Human placenta lysate stained with ARG59021 anti-MMP10 antibody at 0.5 µg/ml, overnight at 4°C.

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