anti-MMP8 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MMP8
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MMP8
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human MMP8.
  • Brand:
CAT.NO. : ARG58047
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MMP8
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MMP8
抗原物种Human
抗原Synthetic peptide derived from Human MMP8.
偶联标记Un-conjugated
別名HNC; PMNL collagenase; MMP-8; PMNL-CL; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; EC 3.4.24.34
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
IP1:50
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Human placenta
实际分子量~ 68 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17394 Mouse MMP8

GeneID: 4317 Human MMP8

GeneID: 63849 Rat MMP8

基因名称MMP8
全名matrix metallopeptidase 8
背景介绍This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
生物功能Can degrade fibrillar type I, II, and III collagens. [UniProt]
细胞定位Secreted > Extracellular space > Extracellular matrix. [UniProt]
预测分子量53 kDa
检测图片 (1)
  • ARG58047 anti-MMP8 antibody WB image

    Western blot: Human placenta lysate stained with ARG58047 anti-MMP8 antibody.

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