anti-MOGS / GCS1 antibody
CAT.NO. : ARG40968
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概述
产品描述 | Rabbit Polyclonal antibody recognizes MOGS / GCS1 |
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反应物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | MOGS / GCS1 |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 1-30 of Human GCS1. |
偶联标记 | Un-conjugated |
別名 | GCS1; DER7; Processing A-glucosidase I; CDG2B; CWH41; Mannosyl-oligosaccharide glucosidase; EC 3.2.1.106 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | 293 | ||||
实际分子量 | 92 kDa |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
抗菌剂 | 0.09% (W/V) Sodium azide. |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q13724 Human Mannosyl-oligosaccharide glucosidase |
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基因名称 | MOGS |
全名 | mannosyl-oligosaccharide glucosidase |
背景介绍 | This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
生物功能 | Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. [UniProt] |
细胞定位 | Endoplasmic reticulum membrane; Single-pass type II membrane protein. [UniProt] |
预测分子量 | 92 kDa |
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