anti-MUC16 / CA125 antibody [X306]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [X306] recognizes MUC16 / CA125
  • 反应物种: Hu
  • 应用: ELISA, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: X306
  • 同位型: IgG1
  • 靶点名称: MUC16 / CA125
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG10534
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Product Details
概述
产品描述Mouse Monoclonal antibody [X306] recognizes MUC16 / CA125
反应物种Hu
应用ELISA, WB
宿主Mouse
克隆Monoclonal
克隆号X306
同位型IgG1
靶点名称MUC16 / CA125
抗原物种Human
抗原MUC16 / CA125 antigen purified from Human ovarian carcinoma.
偶联标记Un-conjugated
別名Mucin-16; MUC-16; Ovarian carcinoma antigen CA125; CA125; Ovarian cancer-related tumor marker CA125; CA-125
应用说明
应用建议
应用推荐稀释比
ELISAAssay-dependent
WBAssay-dependent
应用说明Recommended pairs for sandwich immunoassay (capture-detection):
ARG10534 - ARG10351
ARG10534 - ARG54428
ARG10534 - ARG10156

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Ion exchange chromatography
缓冲液10 mM Tris (pH 7.5), 0.15 M NaCl and 0.05 % Sodium azide
抗菌剂0.05 % Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 94025 Human MUC16

Swiss-port # Q8WXI7 Human Mucin-16

基因名称MUC16
全名mucin 16, cell surface associated
生物功能Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [UniProt]
研究领域Cancer antibody; Controls and Markers antibody; Signaling Transduction antibody
预测分子量1519 kDa
翻译后修饰Heavily O-glycosylated; expresses both type 1 and type 2 core glycans.
Heavily N-glycosylated; expresses primarily high mannose and complex bisecting type N-linked glycans.
May be phosphorylated. Phosphorylation of the intracellular C-terminal domain may induce proteolytic cleavage and the liberation of the extracellular domain into the extracellular space.
May contain numerous disulfide bridges. Association of several molecules of the secreted form may occur through interchain disulfide bridges providing an extraordinarily large gel-like matrix in the extracellular space or in the lumen of secretory ducts.
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