anti-MYBPC1 antibody
CAT.NO. : ARG66552
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概述
产品描述 | Rabbit Polyclonal antibody recognizes MYBPC1 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | MYBPC1 |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide encompassing a sequence within the center region of Human MYBPC1. |
偶联标记 | Un-conjugated |
別名 | LCCS4; MYBPCC; Slow MyBP-C; C-protein, skeletal muscle slow isoform; MYBPCS; Myosin-binding protein C, slow-type |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 30% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q00872 Human Myosin-binding protein C, slow-type |
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基因名称 | MYBPC1 |
全名 | myosin binding protein C, slow type |
背景介绍 | This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
生物功能 | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. [UniProt] |
预测分子量 | 128 kDa |
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