anti-NDP52 antibody [9E2F2]

CAT.NO. : ARG44050

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Size:

50 μg

Product Details

概述

产品描述	Mouse Monoclonal antibody recognizes NDP52
反应物种	Hu, Ms, Rat
应用	FACS, ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	9E2F2
同位型	IgG2b
靶点名称	NDP52
抗原物种	Human
抗原	Recombinant fusion protein containing a sequence corresponding to amino acids 1-446 of Human NDP52.
表达系统	E.coli
偶联标记	Un-conjugated
別名	CALCOCO2; Calcium Binding And Coiled-Coil Domain 2; NDP52; Calcium-Binding And Coiled-Coil Domain-Containing Protein 2; Antigen Nuclear Dot 52 KDa Protein; Nuclear Domain 10 Protein NDP52; Nuclear Domain 10 Protein 52; Nuclear Dot Protein 52; MGC17318

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂	0.05% Sodium azide
稳定剂	4% Trehalose
浓度	0.5 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10241 Human CALCOCO2 GeneID: 76815 Mouse CALCOCO2 Swiss-port # A2A6M5 Mouse Calcium-binding and coiled-coil domain-containing protein 2 Swiss-port # Q13137 Human Calcium-binding and coiled-coil domain-containing protein 2
基因名称	CALCOCO2
全名	Calcium Binding And Coiled-Coil Domain 2
背景介绍	This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
生物功能	Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy.
细胞定位	Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane
预测分子量	52 kDa
翻译后修饰	Phosphoprotein

检测图片 (5)

ARG44050 anti-NDP52 antibody [9E2F2] ICC/IF image
Immunofluorescence: U20S stained with ARG44050 anti-NDP52 antibody [9E2F2] at 5 μg/mL dilution.
ARG44050 anti-NDP52 antibody [9E2F2] WB image
Western blot: Hela, Jurkat and A549 stained with ARG44050 anti-NDP52 antibody [9E2F2] at 0.5 μg/mL dilution.
ARG44050 anti-NDP52 antibody [9E2F2] FACS image
Flow Cytometry: MCF-7 stained with ARG44050 anti-NDP52 antibody [9E2F2] at 1 μg/1x10^6 dilution.
ARG44050 anti-NDP52 antibody [9E2F2] WB image
Western blot: Rat testis stained with ARG44050 anti-NDP52 antibody [9E2F2] at 0.5 μg/mL dilution.
ARG44050 anti-NDP52 antibody [9E2F2] WB image
Western blot: Mouse testis stained with ARG44050 anti-NDP52 antibody [9E2F2] at 0.5 μg/mL dilution.

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