anti-Neurobeachin antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes Neurobeachin
  • 反应物种: Hu, Ms
  • 预测物种: Cow, Dog
  • 应用: IHC-P, WB
  • 特异性: This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Neurobeachin
  • Brand:
CAT.NO. : ARG64081
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes Neurobeachin
反应物种Hu, Ms
预测物种Cow, Dog
应用IHC-P, WB
特异性This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称Neurobeachin
抗原物种Human
抗原C-DFNRWHYEHQNRY
偶联标记Un-conjugated
別名Protein BCL8B; Lysosomal-trafficking regulator 2; Neurobeachin; BCL8B; LYST2
应用说明
应用建议
应用推荐稀释比
IHC-P5 - 10 µg/ml
WB1 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 26422 Mouse NBEA

GeneID: 26960 Human NBEA

Swiss-port # Q8NFP9 Human Neurobeachin

Swiss-port # Q9EPN1 Mouse Neurobeachin

背景介绍This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
研究领域Signaling Transduction antibody
预测分子量328 kDa
检测图片 (2)
  • ARG64081 anti-Neurobeachin antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Cerebral Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64081 anti-Neurobeachin antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG64081 anti-Neurobeachin antibody WB image

    Western blot: HEK293T cells untransfected (left) or transfected with Mouse NBEA (right). Cell lysates were stained with ARG64081 anti-Neurobeachin antibody at 1 µg/ml dilution.

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