anti-NFAT5 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原表位:
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Brand:
CAT.NO. : ARG44880
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NFAT5 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | NFAT5 |
| 抗原物种 | Human |
| 抗原表位 | GQYPVKSEGK ELKIVVQPET QHRARYLTEG SRGSVKDRTQ QGFPTVKLEG HNEPVVLQVF VGNDSGRVKP HGFYQACRVT GRNTTPCKEV DIEGTTVIEV GLDPSNNMTL AVDCVGILKL RNADVEARIG IAGSKKKSTR ARLVFRVNIM RKDGSTLTLQ TPSSPILCTQ PAGVPEILKK SLHSCSVKGE EEVFLIGKNF LKGTKVIFQE NVSDENSWKS EAEIDMELFH QNHLIVKVPP YHDQHITLPV SVGIYVVTNA GRSHDVQPFT |
| 偶联标记 | Un-conjugated |
| 別名 | NFAT5; Nuclear Factor Of Activated T Cells 5; TONEBP; NF-AT5; Nuclear Factor Of Activated T-Cells 5; KIAA0827; NFATL1; OREBP; NFATZ; Nuclear Factor Of Activated T-Cells 5, Tonicity-Responsive; Tonicity-Responsive Enhancer-Binding Protein; T-Cell Transcription Factor NFAT5; TonE-Binding Protein; Tonicity-Responsive Enhancer Binding Protein; Osmotic Response Element-Binding Protein; Glutamine Rich Protein H65; NFAT-Like Protein 1; EC 3.6.3.14; EC 3.6.1; TonEBP |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O94916 Human Nuclear factor of activated T-cells 5 |
|---|---|
| 基因名称 | NFAT5 |
| 全名 | Nuclear Factor Of Activated T Cells 5 |
| 背景介绍 | The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Also involved in the DNA damage response by preventing formation of R-loops; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. [Uniprot] |
| 细胞定位 | Chromosome, Cytoplasm, Nucleus. [Uniprot] |
| 翻译后修饰 | Acetylation, ADP-ribosylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
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