anti-NHERF2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
-
Brand:
CAT.NO. : ARG63842
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes NHERF2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | Please note that this variant has an extra insertion of 11 residues compared to NP_004776.3. The immunizing peptide represents this insertion. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NHERF2 |
| 抗原物种 | Human |
| 抗原 | C-DGSAWKQDPFQ |
| 偶联标记 | Un-conjugated |
| 別名 | Tyrosine kinase activator protein 1; NHE3RF2; E3KARP; Na; +; OCTS2; NHERF-2; Solute carrier family 9 isoform A3 regulatory factor 2; Sodium-hydrogen exchanger regulatory factor 2; NHE3 kinase A regulatory protein E3KARP; NHERF2; SIP-1; SIP1; TKA-1; SRY-interacting protein 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Microwaved tissue section in Tris/EDTA buffer (pH 9.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q15599 Human Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
|---|---|
| 背景介绍 | This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 37 kDa |
检测图片 (2)
ARG63842 anti-NHERF2antibody WB image
Western Blot: human kidney lysate (35 µg protein in RIPA buffer) stained with ARG63842 anti-NHERF2 (isoform a) antibody at 0.3 µg/ml dilution.
ARG63842 anti-NHERF2antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Kidney. (Microwaved antigen retrieval with Tris/EDTA buffer pH9) stained with ARG63842 anti-NHERF2 (isoform a) antibody at 3 µg/ml dilution followed by HRP-staining.
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