anti-Nkx 2.2 antibody [NX2/294]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [NX2/294] recognizes Nkx 2.2
  • 反应物种: Hu, Rat
  • 应用: IHC-P
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: NX2/294
  • 同位型: IgG2b, kappa
  • 靶点名称: Nkx 2.2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56172
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Product Details
概述
产品描述Mouse Monoclonal antibody [NX2/294] recognizes Nkx 2.2
反应物种Hu, Rat
应用IHC-P
宿主Mouse
克隆Monoclonal
克隆号NX2/294
同位型IgG2b, kappa
靶点名称Nkx 2.2
抗原物种Human
抗原Human Nkx2.2 recombinant protein.
偶联标记Un-conjugated
別名Homeobox protein NK-2 homolog B; NKX2.2; Homeobox protein Nkx-2.2; NKX2B
应用说明
应用建议
应用推荐稀释比
IHC-P1 - 2 µg/ml
应用说明IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA.
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4821 Human NKX2-2

Swiss-port # O95096 Human Homeobox protein Nkx-2.2

基因名称NKX2-2
全名NK2 homeobox 2
背景介绍The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008]
生物功能Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]
细胞定位Nuclear
预测分子量30 kDa
检测图片 (3)
  • ARG56172 anti-Nkx 2.2 antibody [NX2/294] IHC-P image

    Immunohistochemistry: Ewing's sarcoma stained with ARG56172 anti-Nkx 2.2 antibody [NX2/294].

  • ARG56172 anti-Nkx 2.2 antibody [NX2/294] IHC-P image

    Immunohistochemistry: Human pancreas stained with ARG56172 anti-Nkx 2.2 antibody [NX2/294].

  • ARG56172 anti-Nkx 2.2 antibody [NX2/294] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Rat pancreas stained with ARG56172 anti-Nkx 2.2 antibody [NX2/294].

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