anti-NPHS2 / Podocin antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
-
Brand:
CAT.NO. : ARG40173
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Size:
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes NPHS2 / Podocin |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Cow, Pig |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NPHS2 / Podocin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminus of Human NPHS2 / Podocin. (C-SPSKPVEPLNPKK, NP_055440.1) |
| 偶联标记 | Un-conjugated |
| 別名 | SRN1; Podocin; PDCN |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPHS2 |
| 全名 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| 背景介绍 | This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. [UniProt] |
| 细胞定位 | Isoform 1: Cell membrane; Peripheral membrane protein. Isoform 2: Endoplasmic reticulum. [UniProt] |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Isoform 2 is glycosylated. [UniProt] |
检测图片 (1)
ARG40173 anti-NPHS2 / Podocin antibody WB image
Western blot: 35 µg of Human kidney and Mouse kidney lysates (in RIPA buffer) stained with ARG40173 anti-NPHS2 / Podocin antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
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