anti-NR5A2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal recognizes NR5A2
  • 反应物种: Hu
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NR5A2
  • 抗原物种: Human
  • 抗原: Human NR5A2 recombinant protein (Position: K192-A508).
  • Brand:
CAT.NO. : ARG44125
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Product Details
概述
产品描述Rabbit Polyclonal recognizes NR5A2
反应物种Hu
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NR5A2
抗原物种Human
抗原Human NR5A2 recombinant protein (Position: K192-A508).
偶联标记Un-conjugated
別名NR5A2; Nuclear Receptor Subfamily 5 Group A Member 2; LRH-1; FTZ-F1beta; FTZ-F1; HB1F-2; HB1F; B1F2; LRH1; FTF; CYP7A Promoter-Binding Factor; B1F; CPF; B1-Binding Factor, Hepatocyte Transcription Factor Which Activates Enhancer II Of Hepatitis B Virus; Nuclear Receptor Subfamily 5, Group A, Member 2; Fetoprotein-Alpha 1 (AFP) Transcription Factor; Alpha-1-Fetoprotein Transcription Factor; Hepatocytic Transcription Factor HB1F-3; Hepatocytic Transcription Factor; Liver Receptor Homolog-1; Liver Receptor Homolog 1; B1-Binding Factor
应用说明
应用建议
应用推荐稀释比
FACS1 - 3 µg/10^6 cells
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2494 Human NR5A2

Swiss-port # O00482 Human Nuclear receptor subfamily 5 group A member 2

基因名称NR5A2
全名Nuclear Receptor Subfamily 5 Group A Member 2
背景介绍The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.
生物功能Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.
细胞定位Nucleus
预测分子量61 kDa
翻译后修饰Isopeptide bond, Ubl conjugation
检测图片 (4)
  • ARG44125 anti-NR5A2 antibody IHC-P image

    Immunohistochemistry: Human parotid acinar cell carcinoma stained with ARG44125 anti-NR5A2 antibody at 2 μg/ml dilution.

  • ARG44125 anti-NR5A2 antibody WB image

    Western blot: HepG2, A549, Caco-2 and 293T stained with ARG44125 anti-NR5A2 antibody at 0.5 μg/ml dilution.

  • ARG44125 anti-NR5A2 antibody FACS image

    Flow Cytometry: CACO-2 stained with ARG44125 anti-NR5A2 antibody at 1 µg/10^6 cells dilution.

  • ARG44125 anti-NR5A2 antibody IHC-P image

    Immunohistochemistry: Human bladder urothelial carcinoma stained with ARG44125 anti-NR5A2 antibody at 2 μg/ml dilution.

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