anti-NSD3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
-
Brand:
CAT.NO. : ARG41984
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NSD3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NSD3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human NSD3. |
| 偶联标记 | Un-conjugated |
| 別名 | Wolf-Hirschhorn syndrome candidate 1-like protein 1; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; EC 2.1.1.43; WHSC1-like protein 1; Histone-lysine N-methyltransferase NSD3; NSD3; Protein whistle; Nuclear SET domain-containing protein 3; pp14328 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q6P2L6 Mouse Histone-lysine N-methyltransferase NSD3 Swiss-port # Q9BZ95 Human Histone-lysine N-methyltransferase NSD3 |
|---|---|
| 基因名称 | WHSC1L1 |
| 全名 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| 背景介绍 | This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015] |
| 生物功能 | Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [UniProt] |
| 细胞定位 | Nucleus. Chromosome. [UniProt] |
| 预测分子量 | 162 kDa |
检测图片 (1)
ARG41984 anti-NSD3 antibody WB image
Western blot: MCF7 cell lysate stained with ARG41984 anti-NSD3 antibody.
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