anti-PAX6 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG55204
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PAX6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAX6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human PAX6 (Swiss: P26367) |
| 偶联标记 | Un-conjugated |
| 別名 | MGDA; Aniridia type II protein; AN; Oculorhombin; Paired box protein Pax-6; AN2; WAGR; FVH1; D11S812E |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | SW480 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PAX6 |
| 全名 | paired box 6 |
| 背景介绍 | This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
| 生物功能 | Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. [UniProt] |
| 产品亮点 | Related products: PAX6 antibodies; Anti-Rabbit IgG secondary antibodies; Related news: Stem cell and the regenerative medicine: Ready for the patients |
| 研究领域 | Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation. |
检测图片 (2)
ARG55204 anti-PAX6 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG55204 anti-PAX6 antibody.
ARG55204 anti-PAX6 antibody WB image
Western blot: SW480 cell lysate stained with ARG55204 anti-PAX6 antibody.
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