anti-PAX6 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes PAX6
  • 反应物种: Ms
  • 预测物种: Hu, Rat
  • 应用: WB
  • 特异性: This antibody is expected to recognise both reported isoforms (NP_000271.1 and NP_001595.2).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PAX6
  • Brand:
CAT.NO. : ARG64256
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes PAX6
反应物种Ms
预测物种Hu, Rat
应用WB
特异性This antibody is expected to recognise both reported isoforms (NP_000271.1 and NP_001595.2).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称PAX6
抗原物种Human
抗原C-REEKLRNQRRQASN
偶联标记Un-conjugated
別名MGDA; Aniridia type II protein; AN; Oculorhombin; Paired box protein Pax-6; AN2; WAGR; FVH1; D11S812E
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 18508 Mouse PAX6

Swiss-port # P63015 Mouse Paired box protein Pax-6

背景介绍This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
研究领域Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
预测分子量47 kDa
翻译后修饰Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation.
检测图片 (1)
  • ARG64256 anti-PAX6 antibody WB image

    Western Blot: Mouse Eye lysate (35 µg protein in RIPA buffer) stained with ARG64256 anti-PAX6 antibody at 0.5 µg/ml dilution.

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