anti-PAX8 antibody [SQab20233]
产品描述 | Recombinant Rabbit Monoclonal antibody [SQab20233] recognizes PAX8 |
---|---|
反应物种 | Hu |
应用 | IHC-P |
宿主 | Rabbit |
克隆 | Monoclonal |
克隆号 | SQab20233 |
同位型 | IgG |
靶点名称 | PAX8 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human PAX8. |
偶联标记 | Un-conjugated |
別名 | Paired box protein Pax-8 |
应用建议 |
| ||||
---|---|---|---|---|---|
应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C - 25°C) for 30 minutes. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
---|---|
纯化 | Purification with Protein A. |
缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05% BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
数据库连接 | |
---|---|
基因名称 | PAX8 |
全名 | paired box 8 |
背景介绍 | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010] |
生物功能 | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. [UniProt] |
细胞定位 | Nucleus. [UniProt] |
预测分子量 | 48 kDa |
ARG66821 anti-PAX8 antibody [SQab20233] WB image (Customer's Feedback)
Western blot: MCF7 cell lysate stained with ARG66821 anti-PAX8 antibody [SQab20233] at 1:1000 dilution.
ARG66821 anti-PAX8 antibody [SQab20233] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human thyroid cancer tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66821 anti-PAX8 antibody [SQab20233].
ARG66821 anti-PAX8 antibody [SQab20233] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human serous cystadenocarcinoma of the ovary tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66821 anti-PAX8 antibody [SQab20233].