anti-PBRM1 / Baf180 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41585
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PBRM1 / Baf180 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PBRM1 / Baf180 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-230 of Human PBRM1 / Baf180 (NP_060783.3). |
| 偶联标记 | Un-conjugated |
| 別名 | hPB1; PB1; Protein polybromo-1; BAF180; Polybromo-1D; BRG1-associated factor 180 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | BT-474 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PBRM1 |
| 全名 | polybromo 1 |
| 背景介绍 | This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012] |
| 生物功能 | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 193 kDa |
检测图片 (1)
ARG41585 anti-PBRM1 / Baf180 antibody WB image
Western blot: 25 µg of BT-474 cell lysate stained with ARG41585 anti-PBRM1 / Baf180 antibody at 1:1000 dilution.
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