anti-PBX1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes PBX1
  • 反应物种: Hu, Ms, Rat
  • 预测物种: Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PBX1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG65262
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes PBX1
反应物种Hu, Ms, Rat
预测物种Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称PBX1
抗原物种Human
抗原C-ATNVSAHGSQANSPS
偶联标记Un-conjugated
別名Homeobox protein PBX1; Pre-B-cell leukemia transcription factor 1; Homeobox protein PRL
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 18514 Mouse PBX1

GeneID: 5087 Human PBX1

Swiss-port # P40424 Human Pre-B-cell leukemia transcription factor 1

Swiss-port # P41778 Mouse Pre-B-cell leukemia transcription factor 1

背景介绍This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
研究领域Developmental Biology antibody; Gene Regulation antibody
预测分子量47 kDa
检测图片 (2)
  • ARG65262 anti-PBX1 antibody WB image

    Western Blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65262 anti-PBX1 antibody at 0.5 µg/ml dilution.

  • ARG65262 anti-PBX1 antibody WB image

    Western Blot: Mouse Eye lysate (35 µg protein in RIPA buffer) stained with ARG65262 anti-PBX1 antibody at 0.5 µg/ml dilution.

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