anti-PCSK6 antibody
CAT.NO. : ARG64704
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概述
产品描述 | Goat Polyclonal antibody recognizes PCSK6 |
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反应物种 | Hu |
应用 | IHC-P |
特异性 | This antibody is expected to recognize reported isoforms a, b, g and h (NP_002561.1; NP_612192.1; NP_612193.1; NP_612194.1 resp.). |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PCSK6 |
抗原物种 | Human |
抗原 | C-YHTFSAHQSRSR |
偶联标记 | Un-conjugated |
別名 | Subtilisin/kexin-like protease PACE4; Subtilisin-like proprotein convertase 4; PACE4; Proprotein convertase subtilisin/kexin type 6; Paired basic amino acid cleaving enzyme 4; EC 3.4.21.-; SPC4 |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P29122 Human Proprotein convertase subtilisin/kexin type 6 |
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背景介绍 | The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
研究领域 | Cell Biology and Cellular Response antibody |
预测分子量 | 106 kDa |
检测图片 (2)
ARG64704 anti-PCSK6 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64704 anti-PCSK6 antibody at 5 µg/ml dilution followed by AP-staining.
ARG64704 anti-PCSK6 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Skeletal Muscle. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64704 anti-PCSK6 antibody at 5 µg/ml dilution followed by AP-staining.
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