anti-Phospholipase A2 V antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG56500
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Phospholipase A2 V |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 特异性 | This antibody does not react to cPLA2, iPLA2 and Human synovial sPLA2 (Type II). |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Phospholipase A2 V |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide around an internal region of Mouse Phospholipase A2 V. |
| 偶联标记 | Un-conjugated |
| 別名 | Group V phospholipase A2; hVPLA(2); FRFB; GV-PLA2; PLA2-10; EC 3.1.1.4; Calcium-dependent phospholipase A2; Phosphatidylcholine 2-acylhydrolase 5 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Pla2g5 |
| 全名 | phospholipase A2, group V |
| 背景介绍 | This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L-alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle. [UniProt] |
| 预测分子量 | 16 kDa |
| 翻译后修饰 | This enzyme lacks one of the seven disulfide bonds found in similar PA2 proteins. |
检测图片 (1)
ARG56500 anti-Phospholipase A2 V antibody WB image
Western blot: 1) 0.025 µg of Recombinant Human sPLA2 (Type V), 2) 0.05 µg of Recombinant Human sPLA2 (Type V), 3) 0.075 µg of Recombinant Human sPLA2 (Type V), 4) 0.1 µg of Recombinant Human sPLA2 (Type V), 5) 0.25 µg of Recombinant Human sPLA2 (Type V), 6) 50 µg of A10 smooth muscle cell lysate (iPLA2), 7) 1 µg of Bee venom PLA2, 8) 1 µg of Human sPLA2 (Type II), 9) 50 µg of HeLa cell lysate (cPLA2), and 10) 0.25 µg of Recombinant Human sPLA2 (Type V) stained with ARG56500 anti-Phospholipase A2 V antibody.
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