anti-PIG3 antibody [1C9]

CAT.NO. : ARG57004

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Size:

50 μl

Product Details

概述

产品描述	Mouse Monoclonal antibody [1C9] recognizes PIG3
反应物种	Hu
应用	ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	1C9
同位型	IgG2a, kappa
靶点名称	PIG3
抗原物种	Human
抗原	Recombinant fragment around aa. 1-332 of Human PIG3.
偶联标记	Un-conjugated
別名	Quinone oxidoreductase PIG3; EC 1.-.-.-; Tumor protein p53-inducible protein 3; PIG3; p53-induced gene 3 protein

应用说明

应用建议

应用	推荐稀释比
ICC/IF	Assay-dependent
WB	1:3000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 9540 Human TP53I3 Swiss-port # Q53FA7 Human Quinone oxidoreductase PIG3
基因名称	TP53I3
全名	tumor protein p53 inducible protein 3
背景介绍	The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
生物功能	May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro). [UniProt]
预测分子量	36 kDa

检测图片 (3)

ARG57004 anti-PIG3 antibody [1C9] ICC/IF image
Immunoflorescense: A549 cell line stained with ARG57004 anti-PIG3 antibody [1C9] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57004 anti-PIG3 antibody [1C9] WB image
Western blot: 40 µg of 1) A549 cell lysate, 2) SW480 cell lysate stained with ARG57004 anti-PIG3 antibody [1C9] at 1:3000.
ARG57004 anti-PIG3 antibody [1C9] WB image
Western blot: 1 µg of 1) 293T cell lysate, 2) TP53I3 Transfected 293T cell lysate stained with ARG57004 anti-PIG3 antibody [1C9] at 1:3000.

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