anti-PITRM1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG56405
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PITRM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PITRM1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human PITRM1 |
| 偶联标记 | Un-conjugated |
| 別名 | Presequence protease, mitochondrial; hPreP; EC 3.4.24.-; Metalloprotease 1; MP1; hMP1; Pitrilysin metalloproteinase 1; PreP |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | U87 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q5JRX3 Human Presequence protease, mitochondrial Swiss-port # Q8K411 Mouse Presequence protease, mitochondrial |
|---|---|
| 基因名称 | PITRM1 |
| 全名 | pitrilysin metallopeptidase 1 |
| 生物功能 | ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. [UniProt] |
| 预测分子量 | 117 kDa |
| 翻译后修饰 | The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions, suggesting that it may participate in redox regulation of the enzyme. |
检测图片 (1)
ARG56405 anti-PITRM1 antibody WB image
Western blot: U87 cell lysate stained with ARG56405 anti-PITRM1 antibody.
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