anti-PLA2G3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44386
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PLA2G3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PLA2G3 |
| 抗原物种 | Human |
| 抗原 | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PLA2G3 |
| 偶联标记 | Un-conjugated |
| 別名 | LA2G3; Phospholipase A2 Group III; GIII-SPLA2; Phosphatidylcholine 2-Acylhydrolase 3; Group 3 Secretory Phospholipase A2; SPLA2-III; Phosphatidylcholine 2-Acylhydrolase GIII; Group III Secretory Phospholipase A2; Group III Secreted Phospholipase A2; Phospholipase A2, Group III; GIII SPLA2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol. |
| 抗菌剂 | 0.01% Thimerosal |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9NZ20 Human Group 3 secretory phospholipase A2 |
|---|---|
| 基因名称 | PLA2G3 |
| 全名 | Phospholipase A2 Group III |
| 背景介绍 | This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. |
| 生物功能 | Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids without apparent head group selectivity. |
| 细胞定位 | Cell membrane, Cytoplasm, Cytoskeleton, Endosome, Membrane, Secreted |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (2)
ARG44386 anti-PLA2G3 antibody WB image
Western blot: 293T stained with ARG44386 anti-PLA2G3 antibody at 1:1000 dilution.
ARG44386 anti-PLA2G3 antibody WB image
Western blot: Mouse liver stained with ARG44386 anti-PLA2G3 antibody at 1:1000 dilution.
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