anti-PSMA1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PSMA1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PSMA1
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human PSMA1
  • Brand:
CAT.NO. : ARG56273
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PSMA1
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PSMA1
抗原物种Human
抗原Recombinant protein of Human PSMA1
偶联标记Un-conjugated
別名HC2; Proteasome subunit alpha type-1; Multicatalytic endopeptidase complex subunit C2; PROS30; Proteasome component C2; 30 kDa prosomal protein; PROS-30; EC 3.4.25.1; HEL-S-275; Proteasome nu chain; NU; Macropain subunit C2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U251
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 26440 Mouse PSMA1

GeneID: 29668 Rat PSMA1

GeneID: 5682 Human PSMA1

基因名称PSMA1
全名proteasome (prosome, macropain) subunit, alpha type, 1
背景介绍The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
生物功能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity). [UniProt]
预测分子量30 kDa
检测图片 (1)
  • ARG56273 anti-PSMA1 antibody WB image

    Western blot: U251 cell lysate stained with ARG56273 anti-PSMA1 antibody.

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