anti-QPCT antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG42658
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes QPCT |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | QPCT |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-361 of Human QPCT (NP_036545.1). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.3.2.5; Glutaminyl cyclase; Glutamyl cyclase; EC; QC; Glutaminyl-peptide cyclotransferase; GCT; sQC; Glutaminyl-tRNA cyclotransferase |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q16769 Human Glutaminyl-peptide cyclotransferase Swiss-port # Q9CYK2 Mouse Glutaminyl-peptide cyclotransferase |
|---|---|
| 基因名称 | QPCT |
| 全名 | glutaminyl-peptide cyclotransferase |
| 背景介绍 | This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008] |
| 生物功能 | Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 41 kDa |
检测图片 (1)
ARG42658 anti-QPCT antibody ICC/IF image
Immunofluorescence: MCF7 cells stained with ARG42658 anti-QPCT antibody.
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