anti-RAB8A antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes RAB8A
  • 反应物种: Hu
  • 预测物种: Cow, Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RAB8A
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64473
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes RAB8A
反应物种Hu
预测物种Cow, Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称RAB8A
抗原物种Human
抗原C-NQGVKITPDQQKR
偶联标记Un-conjugated
別名MEL; Oncogene c-mel; Ras-related protein Rab-8A; RAB8
应用说明
应用建议
应用推荐稀释比
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4218 Human RAB8A

Swiss-port # P61006 Human Ras-related protein Rab-8A

背景介绍The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
研究领域Signaling Transduction antibody
预测分子量24 kDa
检测图片 (1)
  • ARG64473 anti-RAB8A antibody WB image

    Western Blot: Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer) stained with ARG64473 anti-RAB8A antibody at 0.1 µg/ml dilution.

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