anti-RAE1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes RAE1
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog, Pig
  • 应用: IHC-P, WB
  • 特异性: NP_003601and NP_001015885 represent identical proteins.
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RAE1
  • Brand:
CAT.NO. : ARG63811
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes RAE1
反应物种Hu
预测物种Ms, Rat, Cow, Dog, Pig
应用IHC-P, WB
特异性NP_003601and NP_001015885 represent identical proteins.
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称RAE1
抗原物种Human
抗原C-NAAEELKPRNKK
偶联标记Un-conjugated
別名MRNP41; dJ481F12.3; mRNA-associated protein mrnp 41; Mnrp41; MIG14; dJ800J21.1; Rae1 protein homolog; mRNA export factor
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 6 µg/ml
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 8480 Human RAE1

Swiss-port # P78406 Human mRNA export factor

背景介绍Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody; Signaling Transduction antibody
预测分子量41 kDa
检测图片 (3)
  • ARG63811 anti-RAE1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human heart tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63811 anti-RAE1 antibody at 3.75 µg/ml dilution followed by AP-staining.

  • ARG63811 anti-RAE1 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Brain Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63811 anti-RAE1 antibody at 3.8 µg/ml dilution followed by AP-staining.

  • ARG63811 anti-RAE1 antibody WB image

    Western blot: 35 µg of HepG2 (A), HeLa (B), Jurkat (C) and MCF7 (D) lysates (in RIPA buffer) stained with ARG63811 anti-RAE1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.

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