anti-RGS16 antibody
CAT.NO. : ARG41289
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概述
产品描述 | Rabbit Polyclonal antibody recognizes RGS16 |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | RGS16 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-202 of Human RGS16 (NP_002919.3). |
偶联标记 | Un-conjugated |
別名 | RGS16; RGS-r; Retinally abundant regulator of G-protein signaling; Retinal-specific RGS; A28-RGS14P; RGS-R; A28-RGS14; Regulator of G-protein signaling 16; hRGS-r |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Mouse lung | ||||||
实际分子量 | 28 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O15492 Human Regulator of G-protein signaling 16 Swiss-port # P97428 Mouse Regulator of G-protein signaling 16 |
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基因名称 | RGS16 |
全名 | regulator of G-protein signaling 16 |
背景介绍 | The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008] |
生物功能 | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade. [UniProt] |
细胞定位 | Membrane; Lipid-anchor. [UniProt] |
预测分子量 | 23 kDa |
翻译后修饰 | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. [UniProt] |
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