anti-RNF2 / RING1B / BAP1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes RNF2 / RING1B / BAP1
  • 反应物种: Hu
  • 预测物种: Ms, Cow, Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RNF2 / RING1B / BAP1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63505
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes RNF2 / RING1B / BAP1
反应物种Hu
预测物种Ms, Cow, Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称RNF2 / RING1B / BAP1
抗原物种Human
抗原C-PMELYYAPTKEHK
偶联标记Un-conjugated
別名DING; RING1b; RING1B; EC 6.3.2.-; RING finger protein 1B; RING finger protein 2; RING2; RING finger protein BAP-1; BAP-1; HIPI3; BAP1; Protein DinG; E3 ubiquitin-protein ligase RING2; Huntingtin-interacting protein 2-interacting protein 3; HIP2-interacting protein 3
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6045 Human RNF2

Swiss-port # Q99496 Human E3 ubiquitin-protein ligase RING2

背景介绍Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]
产品亮点Related Antibody Duos and Panels:
ARG30309 Polycomb Complexes Antibody Panel (H3K27me3, EZH2, Ring1A, RNF2)
Related products:
RNF2 antibodies; RNF2 Duos / Panels; Anti-Goat IgG secondary antibodies;
研究领域Gene Regulation antibody; Polycomb Complexes antibody
预测分子量38 kDa
翻译后修饰Polyubiquitinated in the presence of UBE2D3 (in vitro).
Monoubiquitinated, by auto-ubiquitination.
检测图片 (1)
  • ARG63505 anti-RNF2 / RING1B / BAP1 antibody WB image

    Western blot: 35 µg of K562 lysate stained with ARG63505 anti-RNF2 / RING1B / BAP1 antibody at 0.5 µg/ml dilution.

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