anti-RNF220 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes RNF220
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RNF220
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 267-566 of Human RNF220 (NP_060620.2).
  • Brand:
CAT.NO. : ARG41588
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes RNF220
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称RNF220
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 267-566 of Human RNF220 (NP_060620.2).
偶联标记Un-conjugated
別名RING finger protein 220; E3 ubiquitin-protein ligase RNF220; EC 6.3.2.-; C1orf164
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse brain
实际分子量~ 72 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 55182 Human RNF220

GeneID: 66743 Mouse RNF220

Swiss-port # Q5VTB9 Human E3 ubiquitin-protein ligase RNF220

Swiss-port # Q6PDX6 Mouse E3 ubiquitin-protein ligase Rnf220

基因名称RNF220
全名ring finger protein 220
生物功能E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. [UniProt]
细胞定位Cytoplasm. [UniProt]
预测分子量63 kDa
翻译后修饰Auto-ubiquitinated; leads to proteasomal degradation. [UniProt]
检测图片 (1)
  • ARG41588 anti-RNF220 antibody WB image

    Western blot: 25 µg of Mouse brain lysate stained with ARG41588 anti-RNF220 antibody at 1:1000 dilution.

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