anti-RNF220 antibody
CAT.NO. : ARG41588
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概述
产品描述 | Rabbit Polyclonal antibody recognizes RNF220 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | RNF220 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 267-566 of Human RNF220 (NP_060620.2). |
偶联标记 | Un-conjugated |
別名 | RING finger protein 220; E3 ubiquitin-protein ligase RNF220; EC 6.3.2.-; C1orf164 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse brain | ||||
实际分子量 | ~ 72 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q5VTB9 Human E3 ubiquitin-protein ligase RNF220 Swiss-port # Q6PDX6 Mouse E3 ubiquitin-protein ligase Rnf220 |
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基因名称 | RNF220 |
全名 | ring finger protein 220 |
生物功能 | E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
预测分子量 | 63 kDa |
翻译后修饰 | Auto-ubiquitinated; leads to proteasomal degradation. [UniProt] |
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