anti-RPS6KA6 / RSK4 antibody
CAT.NO. : ARG42888
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概述
产品描述 | Rabbit Polyclonal antibody recognizes RPS6KA6 / RSK4 |
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反应物种 | Hu |
应用 | FACS, ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | RPS6KA6 / RSK4 |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human RPS6KA6 / RSK4. |
偶联标记 | Un-conjugated |
別名 | Ribosomal S6 kinase 4; pp90RSK4; p90-RSK 6; p90RSK6; RSK-4; PP90RSK4; S6K-alpha-6; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 6; RSK4; Ribosomal protein S6 kinase alpha-6 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
阳性对照 | SH-SY5Y | ||||||||||
实际分子量 | ~ 88 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9UK32 Human Ribosomal protein S6 kinase alpha-6 |
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基因名称 | RPS6KA6 |
全名 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
背景介绍 | This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] |
生物功能 | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. [UniProt] |
细胞定位 | Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic. [UniProt] |
预测分子量 | 84 kDa |
翻译后修饰 | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. [UniProt] |
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