anti-S100A6 antibody
CAT.NO. : ARG41665
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概述
产品描述 | Rabbit Polyclonal antibody recognizes S100A6 |
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反应物种 | Hu, Ms, Rat |
应用 | FACS, ICC/IF, IHC-P, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | S100A6 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human S100A6. |
偶联标记 | Un-conjugated |
別名 | S100 calcium-binding protein A6; PRA; MLN 4; 5B10; Prolactin receptor-associated protein; CACY; Growth factor-inducible protein 2A9; Protein S100-A6; Calcyclin; CABP; 2A9 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
阳性对照 | HeLa | ||||||||||||
实际分子量 | 10 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | S100A6 |
全名 | S100 calcium binding protein A6 |
背景介绍 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] |
生物功能 | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. [UniProt] |
细胞定位 | Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt] |
预测分子量 | 10 kDa |
翻译后修饰 | The N-terminus is blocked. [UniProt] |
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