anti-SCAMP5 antibody
CAT.NO. : ARG44927
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概述
产品描述 | Mouse Monoclonal antibody recognizes SCAMP5 |
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反应物种 | Hu, Ms |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | SCAMP5 |
抗原物种 | Human |
抗原表位 | LPKFIPLKPC FYQDFEADIP |
偶联标记 | Un-conjugated |
別名 | SCAMP5; Secretory Carrier Membrane Protein 5; Secretory Carrier-Associated Membrane Protein 5; MGC24969; HSCAMP5 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q8TAC9 Human Secretory carrier-associated membrane protein 5 Swiss-port # Q9JKD3 Mouse Secretory carrier-associated membrane protein 5 |
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基因名称 | SCAMP5 |
全名 | Secretory Carrier Membrane Protein 5 |
背景介绍 | Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] |
生物功能 | Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway. [UniProt] |
细胞定位 | Cell membrane, Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane, Synapse. [UniProt] |
预测分子量 | 26 kDa |
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