anti-serum Amyloid A antibody [291]
![anti-serum Amyloid A antibody [291]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
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- 应用:
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- 靶点名称:
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CAT.NO. : ARG10047
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [291] recognizes serum Amyloid A |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 特异性 | Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, TGF-β and EGF. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 291 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | serum Amyloid A |
| 抗原物种 | Human |
| 抗原 | Highly purified recombinant human serum Amyloid A (MW: 12 kDa) |
| 偶联标记 | Un-conjugated |
| 別名 | 2-104; 2-103; 2-102; Serum amyloid A-1 protein; TP53I4; SAA; Amyloid fibril protein AA; SAA2; PIG4; 4-101; 3-104 |
应用说明
| 应用说明 | Western Blot: The antibody, when used at concentration of 0.1-0.5μg/mL will allow visualization of 100 ng/lane of recombinant human SAA. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
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| 纯化 | Protein G affinity purified |
| 缓冲液 | 0.01M PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SAA1 |
| 全名 | serum amyloid A1 |
| 背景介绍 | This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012] |
| 生物功能 | Major acute phase protein. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. |
参考文献
克隆号文献
Association of serum amyloid A protein and peptide fragments with prognosis in renal cancer.
WB, IP / Human
Monomeric calgranulins measured by SELDI-TOF mass spectrometry and calprotectin measured by ELISA as biomarkers in arthritis.
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