anti-Serum amyloid P component antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41420
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Serum amyloid P component |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Serum amyloid P component |
| 抗原物种 | Mouse |
| 抗原 | Recombinant protein corresponding to Q21-D224 of Mouse Serum amyloid P component. |
| 偶联标记 | Un-conjugated |
| 別名 | 9.5S alpha-1-glycoprotein; HEL-S-92n; PTX2; Serum amyloid P-component; 1-203; SAP |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 25 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 0.05% Sodium azide. |
| 抗菌剂 | 0.05% Sodium azide |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APCS |
| 全名 | amyloid P component, serum |
| 背景介绍 | The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008] |
| 生物功能 | Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected (PubMed:15174148). [UniProt] |
检测图片 (2)
ARG41420 anti-Serum amyloid P component antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG41420 anti-Serum amyloid P component antibody at 1 µg/ml dilution, overnight at 4°C.
ARG41420 anti-Serum amyloid P component antibody WB image
Western blot: 50 µg of samples under reducing conditions. Mouse liver, Mouse ovary and Mouse testis lysates stained with ARG41420 anti-Serum amyloid P component antibody at 0.5 µg/ml dilution, overnight at 4°C.
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