anti-SLC25A25 / APC3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SLC25A25 / APC3
  • 反应物种: Hu, Ms, Rat
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SLC25A25 / APC3
  • 抗原物种: Human
  • 抗原: Human SLC25A25 / APC3 recombinant protein
  • Brand:
CAT.NO. : ARG44524
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SLC25A25 / APC3
反应物种Hu, Ms, Rat
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SLC25A25 / APC3
抗原物种Human
抗原Human SLC25A25 / APC3 recombinant protein
偶联标记Un-conjugated
別名SLC25A25; Solute Carrier Family 25 Member 25 ; KIAA1896; PCSCL; MCSC; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 25; Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 3; Short Calcium-Binding Mitochondrial Carrier Protein 2; Mitochondrial Adenyl Nucleotide Antiporter SLC25A25; Mitochondrial ATP-Mg/Pi Carrier Protein 3; SCAMC2; Calcium-Binding Mitochondrial Carrier Protein SCaMC-2; Short Calcium-Binding Mitochondrial Carrier 2; Small Calcium-Binding Mitochondrial Carrier 2; SCAMC-2; SCaMC-2; MCSC3; APC3
应用说明
应用建议
应用推荐稀释比
FACS1-3 µg/1x10^6
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 114789 Human SLC25A25

GeneID: 227731 Mouse SLC25A25

GeneID: 246771 Rat SLC25A25

基因名称SLC25A25
全名Solute Carrier Family 25 Member 25
背景介绍The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.
生物功能Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
细胞定位Membrane, Mitochondrion, Mitochondrion inner membrane
预测分子量53 kDa
检测图片 (5)
  • ARG44524 anti-SLC25A25 / APC3 antibody IHC-P image

    Immunohistochemistry: Human prostate cancer stained with ARG44524 anti-SLC25A25 / APC3 antibody at 2 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: K562, SiHa, Jurkat and MCF-7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody FACS image

    Flow Cytometry: JK stained with ARG44524 anti-SLC25A25 / APC3 antibody at 1 μg/10^6 cells dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: Rat liver stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.

  • ARG44524 anti-SLC25A25 / APC3 antibody WB image

    Western blot: RAW264.7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.

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