anti-Slug antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG55242
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Slug |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Slug |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 98-129 (Center) of Human Slug. |
| 偶联标记 | Un-conjugated |
| 別名 | Protein snail homolog 2; SNAIL2; WS2D; Neural crest transcription factor Slug; Zinc finger protein SNAI2; SLUG; SLUGH1 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse heart |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SNAI2 |
| 全名 | snail family zinc finger 2 |
| 背景介绍 | SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects. |
| 研究领域 | Cancer antibody; Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | GSK3B-mediated phosphorylation results in cytoplasmic localization and degradation. |
检测图片 (3)
ARG55242 anti-Slug antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG55242 anti-Slug antibody (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI (blue) for nuclear staining.
ARG55242 anti-Slug antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human Breast tissue stained with ARG55242 anti-Slug antibody.
ARG55242 anti-Slug antibody WB image
Western blot: 20 µg of Mouse heart lysate stained with ARG55242 anti-Slug antibody at 1:2000 dilution.
参考文献
Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.
WB / Human
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