anti-STAG2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes STAG2
  • 反应物种: Hu, Ms, Rat
  • 预测物种: Cow, Dog, Pig
  • 应用: WB
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_001036214.1; NP_006594.3). Reported variants NP_001036215.1 and NP_001036214.1 represent identical protein:Reported variants NP_001036216.1 and NP_006594.3 represent identical protein.
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: STAG2
  • Brand:
CAT.NO. : ARG65049
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes STAG2
反应物种Hu, Ms, Rat
预测物种Cow, Dog, Pig
应用WB
特异性This antibody is expected to recognize both reported isoforms (NP_001036214.1; NP_006594.3). Reported variants NP_001036215.1 and NP_001036214.1 represent identical protein:Reported variants NP_001036216.1 and NP_006594.3 represent identical protein.
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称STAG2
抗原物种Human
抗原C-SRGSTVRSKKSKPST
偶联标记Un-conjugated
別名SCC3 homolog 2; bA517O1.1; Stromal antigen 2; SA-2; Cohesin subunit SA-2; SA2; SCC3B
应用说明
应用建议
应用推荐稀释比
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10735 Human STAG2

GeneID: 20843 Mouse STAG2

Swiss-port # O35638 Mouse Cohesin subunit SA-2

Swiss-port # Q8N3U4 Human Cohesin subunit SA-2

背景介绍The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
研究领域Cell Biology and Cellular Response antibody; Gene Regulation antibody
预测分子量141 kDa
翻译后修饰Phosphorylated by PLK1. The large dissociation of cohesin from chromosome arms during prophase is partly due to its phosphorylation (By similarity).
检测图片 (2)
  • ARG65049 anti-STAG2 antibody WB image

    Western blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65049 anti-STAG2 antibody at 0.03 µg/ml dilution.

  • ARG65049 anti-STAG2 antibody WB image

    Western blot: Mouse Spleen (A), Mouse Thymus (B) and Rat Spleen (C) lysates (35 µg protein in RIPA buffer) stained with ARG65049 anti-STAG2 antibody at 0.3 µg/ml dilution.

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