anti-STS / Arylsulfatase C antibody
CAT.NO. : ARG42643
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概述
产品描述 | Rabbit Polyclonal antibody recognizes STS / Arylsulfatase C |
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反应物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | STS / Arylsulfatase C |
抗原物种 | Human |
抗原 | Recombinant protein corresponding to K297-E396 of Human STS / Arylsulfatase C. |
偶联标记 | Un-conjugated |
別名 | XLI; ARSC; Steroid sulfatase; SSDD; Steryl-sulfate sulfohydrolase; ASC; Steryl-sulfatase; Arylsulfatase C; EC 3.1.6.2; ARSC1; ES |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
实际分子量 | ~ 65 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | STS |
全名 | steroid sulfatase (microsomal), isozyme S |
背景介绍 | This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016] |
生物功能 | Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. [UniProt] |
细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
预测分子量 | 65 kDa |
翻译后修饰 | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. [UniProt] |
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