anti-Synaptophysin antibody [SQab19147]

Key features and details

  • 产品描述: Recombinant Rabbit Monoclonal antibody [SQab19147] recognizes Synaptophysin
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SQab19147
  • 同位型: IgG
  • 靶点名称: Synaptophysin
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG66629
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Product Details
概述
产品描述Recombinant Rabbit Monoclonal antibody [SQab19147] recognizes Synaptophysin
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Monoclonal
克隆号SQab19147
同位型IgG
靶点名称Synaptophysin
抗原物种Human
抗原Synthetic peptide within aa. 213-313 of Human Synaptophysin.
偶联标记Un-conjugated
別名Synaptophysin; MRXSYP; Major synaptic vesicle protein p38; MRX96
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:200
WB1:500
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C - 25°C) for 30 minutes.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20977 Mouse SYP

GeneID: 24804 Rat SYP

GeneID: 6855 Human SYP

基因名称SYP
全名synaptophysin
背景介绍This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011]
生物功能Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). [UniProt]
细胞定位Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. [UniProt]
预测分子量34 kDa
翻译后修饰Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. [UniProt]
检测图片 (2)
  • ARG66629 anti-Synaptophysin antibody [SQab19147] WB image

    Western blot: 20 μg of Mouse brain and Rat brain lysates stained with ARG66629 anti-Synaptophysin antibody [SQab19147] at 1:500 dilution.

  • ARG66629 anti-Synaptophysin antibody [SQab19147] IHC-P image

    Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human glioma tissue stained with ARG66629 anti-Synaptophysin antibody [SQab19147]. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).

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