anti-TCTN2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TCTN2
  • 反应物种: Hu, Ms
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TCTN2
  • 抗原: Synthetic peptide (15 aa) within aa. 610-660 of Human TCTN2.
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG54662
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TCTN2
反应物种Hu, Ms
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TCTN2
抗原Synthetic peptide (15 aa) within aa. 610-660 of Human TCTN2.
偶联标记Un-conjugated
別名Tectonic-2; MKS8; TECT2; C12orf38
应用说明
应用建议
应用推荐稀释比
ELISAAssay-Dependent
WB1 μg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照SK-N-SH Cell Lysate
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 67978 Mouse TCTN2

GeneID: 79867 Human TCTN2

Swiss-port # Q2MV57 Mouse Tectonic-2

Swiss-port # Q96GX1 Human Tectonic-2

基因名称TCTN2
全名tectonic family member 2
背景介绍TCTN2 Antibody: TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube. |
研究领域Cell Biology and Cellular Response antibody
预测分子量77 kDa
检测图片 (1)
  • ARG54662 anti-TCTN2 antibody WB image

    Western blot: SK-N-SH cell lysate stained with ARG54662 anti-TCTN2 antibody at 1 μg/ml.

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