anti-TPP1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes TPP1
  • 反应物种: Hu
  • 预测物种: Cow, Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TPP1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64974
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes TPP1
反应物种Hu
预测物种Cow, Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称TPP1
抗原物种Human
抗原C-TPSVIRKRYNLTSQD
偶联标记Un-conjugated
別名EC 3.4.14.9; TPP-1; Tripeptidyl-peptidase I; GIG1; Lysosomal pepstatin-insensitive protease; SCAR7; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase 1; CLN2; LPIC; Cell growth-inhibiting gene 1 protein; TPP-I
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1200 Human TPP1

Swiss-port # O14773 Human Tripeptidyl-peptidase 1

背景介绍This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Neuroscience antibody
预测分子量61 kDa
翻译后修饰Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity.
检测图片 (1)
  • ARG64974 anti-TPP1 antibody WB image

    Western blot: 35 µg of Human Placenta lysate stained with ARG64974 anti-TPP1 antibody at 0.3 µg/ml dilution.

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