anti-Transferrin antibody [11D3]
![anti-Transferrin antibody [11D3]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
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- 克隆:
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- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG10445
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [11D3] recognizes Transferrin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 11D3 |
| 同位型 | IgG1 |
| 靶点名称 | Transferrin |
| 抗原物种 | Human |
| 抗原 | Placental transferrin receptor or transferrin |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-1 metal-binding globulin; Siderophilin; Transferrin; PRO1557; TFQTL1; Serotransferrin; PRO2086 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A affinity purified |
| 缓冲液 | PBS and 0.1 % Sodium azide |
| 抗菌剂 | 0.1 % Sodium azide |
| 浓度 | 1.0-2.0 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TF |
| 全名 | transferrin |
| 背景介绍 | Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] |
| 生物功能 | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody |
| 预测分子量 | 77 kDa |
参考文献
克隆号文献
Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation.
Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake.
WB, ELISA /
Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach.
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