anti-TREM1 antibody [6B1]
CAT.NO. : ARG43857
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概述
产品描述 | Mouse Monoclonal antibody recognizes TREM1. |
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反应物种 | Hu |
应用 | ELISA, FACS, WB |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 6B1 |
同位型 | IgG1 |
靶点名称 | TREM1 |
抗原物种 | Human |
抗原 | Human TREM1 recombinant protein. |
偶联标记 | Un-conjugated |
Protein Full name | Triggering receptor expressed on myeloid cells 1 |
別名 | TREM1; Triggering Receptor Expressed On Myeloid Cells 1; TREM-1; CD354; Triggering Receptor Expressed On Monocytes 1; CD354 Antigen |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein-A affinity chromatography |
缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
抗菌剂 | 15 mM Sodium azide |
浓度 | 1 mg/ml |
存放说明 | Protect from prolonged exposure to light. Do not freeze. |
生物信息
数据库连接 | Swiss-port # Q9NP99 Human Triggering receptor expressed on myeloid cells 1 |
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基因名称 | TREM1 |
全名 | Triggering Receptor Expressed On Myeloid Cells 1 |
背景介绍 | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
生物功能 | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. [UniProt] |
细胞定位 | Cell membrane, Membrane, Secreted |
预测分子量 | 26 kDa |
翻译后修饰 | Disulfide bond; Glycoprotein |
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