anti-TREM1 antibody
CAT.NO. : ARG58762
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概述
产品描述 | Rabbit Polyclonal antibody recognizes TREM1 |
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反应物种 | Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | TREM1 |
抗原物种 | Mouse |
抗原 | Synthetic peptide corresponding to aa. 74-90 of Mouse TREM1 (FTRPSEVHMGKFTLKHD). |
偶联标记 | Un-conjugated |
別名 | TREM-1; CD antigen CD354; CD354; Triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells 1 |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
稳定剂 | 5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9JKE2 Mouse Triggering receptor expressed on myeloid cells 1 |
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基因名称 | TREM1 |
全名 | triggering receptor expressed on myeloid cells 1 |
背景介绍 | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
生物功能 | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. [UniProt] |
细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
预测分子量 | 26 kDa |
翻译后修饰 | Glycosylated. [UniProt] |
检测图片 (3)
ARG58762 anti-TREM1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse spleen tissue stained with ARG58762 anti-TREM1 antibody.
ARG58762 anti-TREM1 antibody WB image
Western blot: 1 ng of Recombinant Mouse TREM1 Protein stained with ARG58762 anti-TREM1 antibody.
ARG58762 anti-TREM1 antibody WB image
Western blot: 50 µg of sample under reducing conditions. Rat liver, Mouse liver and Mouse spleen lysates stained with ARG58762 anti-TREM1 antibody at 0.5 µg/ml dilution, overnight at 4°C.
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