anti-TRIM65 antibody
CAT.NO. : ARG44970
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概述
产品描述 | Mouse Monoclonal antibody recognizes TRIM65 |
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反应物种 | Hu |
应用 | WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | TRIM65 |
抗原物种 | Human |
抗原表位 | DAERLKREAQ LRASLEVTQQ QATQAEGQLL ELRKQSSQIQ NSACILASWV SGKFSSLLQA LEIQHTTALR SIEVAKTQAL AQARDEEQRL RVHLEAVARH GCRIRELLEQ VDEQTFLQES QLLQPPGPLG PLTPLQWDED QQLGDLKQLL SRLCGLLLEE GSHPGAPAKP VDLAPVEAPG |
偶联标记 | Un-conjugated |
別名 | TRIM65; Tripartite Motif Containing 65; Tripartite Motif-Containing Protein 65; E3 Ubiquitin-Protein Ligase TRIM65; Tripartite Motif-Containing 65; 4732463G12Rik; EC 2.3.2.27 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q6PJ69 Human Tripartite motif-containing protein 65 |
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基因名称 | TRIM65 |
全名 | Tripartite Motif Containing 65 |
背景介绍 | Predicted to enable zinc ion binding activity. Involved in positive regulation of autophagy. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
生物功能 | In addition, negatively regulates inflammasome activation by promoting 'lys48'-linked ubiquitination of NLRP3 which is critical for the inhibition of NLRP3 inflammasome activation in resting macrophages. [Uniprot] |
细胞定位 | Cytoplasm. [Uniprot] |
翻译后修饰 | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
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